Bisphospho-bloody-amazing-phates!

As I have bone metastases, ‘bone pain’ was the first symptom I had that showed I was in trouble. Symptoms were a leg that felt strained at the top, and made we walk like a table, and REALLY bad back ache.
I’ve now finished chemo and radio therapies, but ongoing (till it ‘stops working’ – don’t like the sound of that) I’m having monthly infusions of bisphosphonate. I don’t quite understand how it works – it stops my clasts blasting* or something – but the results are fantastic.
The positive effect seems to have built a little with each infusion, and this week I’m delighted to announce that I feel ‘normal’, except that my ‘normal’ is better than it used to be because I’m 70lbs lighter. On Monday I walked 7 miles, and helped to water the allotment, which is a back breaking task even for a healthy individual. Tuesday it was just a 3 mile walk, with more watering. It’s hard to remember I could barely walk across the room a year ago, and couldn’t even put on my own pants. I used to try to don my pants with a walking stick, but it always ended in hopeless twiddling, like one of those plates on sticks stunts beloved by circuses.
I just wanted to put a little positive note up here, because so many of us write about gruelling treatments etc, but rarely write about their effects, and how sometimes they actually work!

*Bone undergoes constant turnover and is kept in balance (homeostasis) by osteoblasts creating bone and osteoclasts destroying bone. Bisphosphonates inhibit the digestion of bone by encouraging osteoclasts to undergo apoptosis, or cell death, thereby slowing bone loss. (Wikipedia)

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5 responses to “Bisphospho-bloody-amazing-phates!

  1. You are so amazing Vicky. I love reading your blog it is interesting and informative. You are doing a great job by writing this thank you.xx

  2. I am so surprised and sorry to hear your cancer has metastasized. As expected, you’re up front about it and optimistic. I really admire how you deal with your disease. I’ll keep you in my prayers.

  3. I’m so glad the biophosphonate is having this positive effect Vicky. It really is good to see a drug doing what it’s meant to without causing other untoward effects. I’m truly sorry that you’re having to live with mets but I’m so glad that you’re felling good and keeping them in check. Long may that continue!

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